EvoGenArch
Evolution of the genetic architecture of quantitative traits
Part of the ERC Starting Grant that takes place from September 1, 2024 to August 31, 2029.
Pierre de Villemereuil
Pierre de Villemereuil conducts research on the genetics of adaptation, at the frontier between evolutionary biology, genetics and statistical methods.
His research interests focus on the study of adaptive phenomena in natural populations. To do this, he combines approaches from evolutionary ecology, quantitative genetics and population genomics.
His work requires the development of new methodological frameworks and statistical tools, for which he mainly uses Bayesian statistics.
Project summary
This ERC Starting Grant project proposes, over 5 years, to improve our ability to empirically study the genetic architecture of phenotypic traits and the link between evolution and genetic architecture, and to do so in three stages:
- Developing a new statistical method that is explicitly focused on the inference of genetic architecture, i.e. the diversity of mutation effects;
- Studying in depth the link between natural selection and genetic architecture of different phenotypic traits at the intra- and inter-population scale on a model species in evolutionary ecology: the viviparous lizard;
- Comparing the natural selection, demographic effects and genetic architecture of different phenotypic traits in more than 20 species of animals and plants.